Development and Commissioning of a Small-Scale, Modular and Integrated Plant for the Quasi-Continuous Production of Crystalline Particles

Increasing global competition, volatile markets and the demand for individual products challenge companies in almost all business sectors require innovative solutions. In chemical pharmaceutical industries, these include modular design, integration of several unit operations one apparatus development small-scale, versatile multipurpose plants. An example such a modular, integrated small-scale system is belt crystallizer. This device combines process steps cooling crystallization, solid-liquid separation contact drying single plant. The basis filter which vacuum trays below medium are replaced by temperature control filtration units. Due to identical dimensions, it possible arrange functional units any order, turn allows high degree flexibility rapid adaptation customer requirements. Within scope publication, commissioning crystallizer takes place. First all, general functionality plant concept demonstrated using sucrose as model system. Further experiments show that particle size distribution width manufactured crystals can be specifically influenced selected parameters, e.g., profile during residence time.